Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 5/20 | 0.62 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | RARB | P10826 | 1/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525848 | 1.00 | CXCR1 (0.62) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL3151143 | 0.89 | CXCR1 (0.62) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL19995668 | 0.89 | CXCR1 (0.62) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL24045918 | 0.89 | CXCR1 (0.62) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL24045928 | 0.89 | CXCR1 (0.62) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL24045927 | 0.87 | MME (0.61) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL27785981 | 0.87 | MME (0.61) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL12336396 | 0.86 | CXCR1 (0.62) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL3152281 | 0.86 | CXCR1 (0.62) | CXCR1CXCR2PTGS1PTGS2LMNA | |
| SCHEMBL6449599 | 0.85 | CXCR1 (0.57) | CXCR1CXCR2PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255164-B1 | A thioester and its use for preparing pharmaceutical compositions for the treatment of ischemia and reperfusion syndromes | ZAMBON SPA (IT) | 1993-10-20 | — | — | EP | claimed |