Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456816 | 1.00 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1LTB4RLTB4R2PPARG | |
| SCHEMBL450282 | 0.85 | FFAR4 (0.61) | PPARGPPARAFFAR4FFAR1 | |
| SCHEMBL2482140 | 0.85 | FFAR4 (0.61) | PPARGPPARAFFAR4FFAR1 | |
| SCHEMBL2483044 | 0.85 | FFAR4 (0.61) | PPARGPPARAFFAR4FFAR1 | |
| SCHEMBL17332277 | 0.85 | FFAR4 (0.61) | PPARGPPARAFFAR4FFAR1 | |
| SCHEMBL23288411 | 0.85 | FFAR4 (0.61) | PPARGPPARAFFAR4FFAR1 | |
| SCHEMBL23288472 | 0.84 | FFAR4 (0.59) | PPARGPPARAFFAR4FFAR1 | |
| SCHEMBL27262058 | 0.84 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1PPARGPPARAFFAR4 | |
| SCHEMBL25170031 | 0.84 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1PPARGPPARAFFAR4 | |
| SCHEMBL9529521 | 0.83 | FFAR4 (0.69) | CYSLTR2CYSLTR1LTB4RFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419610-B1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | claimed |