Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.61 |
| ▸ | PDE4A | P27815 | 9/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.61 |
| ▸ | PDE5A | O76074 | 5/20 | 0.53 |
| ▸ | PDE1A | P54750 | 2/20 | 0.53 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.53 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332380 | 0.88 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL9530020 | 0.82 | PDE4D (0.59) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7379219 | 0.81 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9525887 | 0.79 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7340940 | 0.77 | PDE4D (0.77) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7334985 | 0.76 | PDE4D (0.77) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7334292 | 0.76 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL73755 | 0.75 | PDE4D (0.55) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7362898 | 0.75 | PDE4D (0.59) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7335862 | 0.75 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569414-A1 | BENZAMIDES | RHONE-POULENC RORER LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |
| WO-1992012961-A1 | BENZAMIDES | RHONE POULENC RORER LIMITED (GB) | 1992-08-06 | — | — | WO | disclosed |