Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3036904 | 0.84 | MEN1 (0.64) | MEN1KMT2AGAAMAPK14CASP6 | |
| SCHEMBL1032873 | 0.84 | MEN1 (0.64) | MEN1KMT2AGAACASP6MAPT | |
| SCHEMBL13941167 | 0.82 | MEN1 (0.77) | MEN1KMT2AGAAMAPK14CASP6 | |
| SCHEMBL29651988 | 0.81 | GAA (0.59) | MEN1KMT2AGAAMAPK14CASP6 | |
| SCHEMBL2982634 | 0.81 | GAA (0.59) | MEN1KMT2AGAAMAPK14CASP6 | |
| SCHEMBL3020598 | 0.79 | MEN1 (1.00) | MEN1KMT2AGAACASP6MAPT | |
| SCHEMBL7165264 | 0.79 | HPGD (0.53) | MEN1KMT2AGAAMAPK14CASP6 | |
| SCHEMBL10744425 | 0.78 | HPGD (0.65) | MEN1KMT2AGAACASP6HPGD | |
| SCHEMBL8543123 | 0.77 | KMT2A (0.56) | MEN1KMT2AGAAMAPK14CASP6 | |
| SCHEMBL1033075 | 0.75 | MEN1 (0.54) | MEN1KMT2AGAAMAPK14CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523046-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA 2? AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5159085-A | Antiinflammatory, antiallergens, cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-5021576-A | Antiinflammatory, antiarthritic, hypotensive, anticarcinogenic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| WO-1991006539-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-16 | — | — | WO | disclosed |