SCHEMBL952595

SCHEMBL952595

Clc1ccncc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31145055 1.00
Hydrochloric Acid SCHEMBL7614092 0.97
Methane SCHEMBL27881196 0.97
Formamide SCHEMBL27780436 0.85 GAA (0.52)
SCHEMBL30350188 0.79 CDC25B (0.50)
SCHEMBL31301252 0.79 GSK3B (0.59)
SCHEMBL2942923 0.79 CDC25B (0.50)
SCHEMBL29530920 0.77
SCHEMBL317186 0.77
SCHEMBL8354714 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000692-A1 Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors AURIGENE ONCOLOGY LIMITED (IN) 2026-01-01 US claimed
EP-1619184-A2 Urea compounds as kinase inhibitors Amgen, Inc. (US) 2006-01-25 EP claimed
US-6645990-B2 For prophylaxis and therapy of diseases, such as cell proliferation or apoptosis mediated diseases AMGEN INC. 2003-11-11 US claimed
US-20020173507-A1 Urea compounds and methods of uses AMGEN INC. 2002-11-21 US claimed
US-12595273-B2 Phosphonate conjugates and uses thereof TRANSLATIONAL GENOMICS RES INST (US) 2026-04-07 US disclosed
US-20260090879-A1 HEART VALVE PROSTHESES WITH A DRUG ELUTING MECHANISM NAT UNIV SINGAPORE (SG) 2026-04-02 US disclosed
US-20250320184-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2025-10-16 US disclosed
US-12441724-B2 Inhibitors of plasma kallikrein and uses thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-10-14 US disclosed
EP-4586966-A1 HEART VALVE PROSTHESES WITH A DRUG ELUTING MECHANISM National University of Singapore (SG) 2025-07-23 EP disclosed
WO-2025125297-A1 COMPOUND, ORGANIC LIGHT EMITTING DIODE, AND DISPLAY DEVICE NOVALED GMBH (DE) 2025-06-19 WO disclosed
EP-4572585-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE Novaled GmbH (DE) 2025-06-18 EP disclosed
US-20250179079-A1 HEXAHYDROPYRIDO[4,3-B]INDOLYL KETONE DERIVATIVES USEFUL AS CGAS MODULATORS VENTUS THERAPEUTICS U.S., INC. (US) 2025-06-05 US disclosed
US-5039811-A Analgesics, antidepressants, memory activators; condensation, reduction HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-08-13 US disclosed
US-4970218-A ANALGESIC, ANTIDEPRESSANT, MEMORY ENHANCEMENT HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1990-11-13 US disclosed
EP-0140322-B1 POLYMER CATALYST TRANSDUCERS AND USE THEREOF IN TEST KITS FOR ANALYTICAL METHODS MILES INC. (US) 1989-01-25 EP disclosed
US-4560534-A Polymer catalyst transducers MILES LABORATORIES, INC. (US) 1985-12-24 US disclosed
EP-0140322-A2 Polymer catalyst transducers and use thereof in test kits for analytical methods MILES INC. (US) 1985-05-08 EP disclosed
US-4310671-A IN THE PRESENCE OF OLEUM OLIN CORPORATION (US) 1982-01-12 US disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed