Ethylene

Ethylene

SCHEMBL9526172

C=C.O=C(O)S.O=C(O)S.O=C(O)S.S.S.S.S

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
LMNA P02545 2/20 0.33
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
ABCB11 O95342 1/20 0.31
F2 P00734 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
KMT2A Q03164 1/20 0.31
DUSP3 P51452 1/20 0.31
PTPN5 P54829 1/20 0.31
PTPN11 Q06124 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL28284006 0.89
SCHEMBL7125892 0.84 CA1 (0.50) CA1CA2CA9LMNAHPGD
SCHEMBL5146466 0.84 CA1 (0.50) CA1CA2CA9LMNAHPGD
SCHEMBL28780148 0.84
SCHEMBL27075 0.84
SCHEMBL1907850 0.78
SCHEMBL5574221 0.78
SCHEMBL8641356 0.78
SCHEMBL9805534 0.78 CA1 (0.44) CA1CA2CA9LMNAHPGD
SCHEMBL10826030 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0171926-B1 DYNAMICALLY CURED THERMOPLASTIC OLEFIN POLYMERS ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1993-03-31 EP disclosed
US-5086121-A Vulcanizing rubber mixture, blending in at least one second rubber at temperature above softening point of the polyolefin ADVANCED ELASTOMER SYSTEMS, L. P. (US) 1992-02-04 US disclosed
EP-0172645-B1 HEAT-SHRINKABLE THERMOPLASTIC POLYOLEFIN COMPOSITION ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1991-08-14 EP disclosed
US-4960830-A BLEND OF POLYOLEFIN, WITH CURED AND UNCURED RUBBER EXXON RESEARCH AND ENGINEERING COMPANY (US) 1990-10-02 US disclosed
US-4845145-A GASKETS EXXON RESEARCH & ENGINEERING COMPANY (US) 1989-07-04 US disclosed
US-4639487-A ETHYLENE COPOLYMER, BUTYL RUBBER EXXON RESEARCH & ENGINEERING CO. (US) 1987-01-27 US disclosed
US-4607074-A BLENDED WITH ONE VULCANIZED AND AT LEAST ONE UNVULACNIZED RUBBER EXXON RESEARCH & ENGINEERING CO. (US) 1986-08-19 US disclosed
EP-0190497-A2 Dynamically cured thermoplastic olefin polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-08-13 EP disclosed
US-4593062-A Blend of an olefin resin, halogenated butyl rubber and neoprene EXXON RESEARCH & ENGINEERING CO. (US) 1986-06-03 US disclosed
EP-0172645-A2 Heat-shrinkable thermoplastic polyolefin composition ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1986-02-26 EP disclosed
EP-0171926-A2 Dynamically cured thermoplastic olefin polymers ADVANCED ELASTOMER SYSTEMS, L.P. (US) 1986-02-19 EP disclosed