Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525947 | 0.89 | NPC1 (0.39) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| Hydrochloric Acid SCHEMBL9524299 | 0.85 | NPC1 (0.37) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL9526289 | 0.83 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL9525476 | 0.83 | POLB (0.46) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL9525183 | 0.82 | POLB (0.45) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL10401397 | 0.82 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL9525526 | 0.81 | POLB (0.44) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL9525171 | 0.81 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL9525705 | 0.81 | NPC1 (0.47) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL10401423 | 0.81 | NPC1 (0.40) | SMN1; SMN2NPC1RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |