Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | CLK2 | P49760 | 1/20 | 0.71 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458734 | 0.91 | KDM4E (0.75) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Water SCHEMBL9773846 | 0.90 | KDM4E (0.74) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9773974 | 0.90 | KDM4E (0.71) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL5567734 | 0.89 | KCNH2 (0.74) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Water SCHEMBL9773796 | 0.89 | KDM4E (0.73) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Water SCHEMBL9773800 | 0.89 | KDM4E (0.73) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL9522855 | 0.89 | KCNH2 (0.59) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| Water SCHEMBL9773903 | 0.89 | KCNH2 (0.73) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL14749181 | 0.88 | KDM4E (0.70) | KCNH2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL680655 | 0.88 | KDM4E (0.70) | KCNH2KDM4EALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571400-A1 | NOVEL QUINOLONE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO.,LTD. (KR) | 1993-12-01 | — | — | EP | disclosed |
| WO-1992012155-A1 | NOVEL QUINOLONE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | HANMI PHARMACEUTICAL CO., LTD. (KR) | 1992-07-23 | — | — | WO | disclosed |