Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | SCN1A | P35498 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.59 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812545 | 0.88 | HRH1 (0.73) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL8812539 | 0.88 | HRH1 (0.73) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL894817 | 0.88 | HRH1 (0.73) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL15873671 | 0.79 | HRH1 (0.68) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL4425169 | 0.78 | HRH1 (0.61) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL2238914 | 0.78 | CYP2D6 (0.66) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL28257085 | 0.78 | CYP2D6 (0.66) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL1878869 | 0.76 | CYP19A1 (0.55) | HRH1MEN1LMNACYP2D6SCN1A | |
| Azacyclonol SCHEMBL1648657 | 0.76 | HRH1 (0.93) | HRH1MEN1LMNACYP2D6SCN1A | |
| SCHEMBL11682493 | 0.75 | CYP19A1 (0.62) | HRH1MEN1LMNACYP2D6SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0231996-B1 | NOVEL AMINO ACID DERIVATIVES | NOVO NORDISK A/S (DK) | 1993-10-06 | — | — | EP | disclosed |
| EP-0231996-A2 | Novel amino acid derivatives | NOVO NORDISK A/S (DK) | 1987-08-12 | — | — | EP | disclosed |