Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526581 | 0.91 | ACE (0.53) | ACE | |
| SCHEMBL9525032 | 0.87 | ACE (0.46) | ACE | |
| SCHEMBL9526161 | 0.85 | ACE (0.62) | ACE | |
| SCHEMBL9527243 | 0.85 | ACE (0.62) | ACE | |
| SCHEMBL9526495 | 0.85 | ACE (0.62) | ACE | |
| SCHEMBL9526504 | 0.85 | ACE (0.62) | ACE | |
| SCHEMBL9526487 | 0.85 | ACE (0.62) | ACE | |
| SCHEMBL10641610 | 0.84 | ACE (0.57) | ACE | |
| SCHEMBL9527864 | 0.82 | ACE (0.51) | ACE | |
| SCHEMBL9526566 | 0.81 | ACE (0.49) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365045-B1 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-12-01 | — | — | EP | disclosed |
| EP-0365045-A1 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1990-04-25 | — | — | EP | disclosed |
| US-4699905-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0161801-A2 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |