Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526496 | 0.94 | KDM4E (0.35) | KDM4EALDH1A1HPGDSMN1; SMN2PTGER4 | |
| SCHEMBL9529516 | 0.86 | MAPT (0.45) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL305026 | 0.85 | BACE1 (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL29113309 | 0.81 | MAPT (0.53) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL9526961 | 0.81 | PTGER4 (0.31) | SMN1; SMN2PTGER4PTGER3PTGER2BACE1 | |
| SCHEMBL29113341 | 0.81 | MAPT (0.53) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL29688905 | 0.81 | MAPT (0.53) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL29689139 | 0.81 | MAPT (0.53) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL29113316 | 0.81 | MAPT (0.53) | ALDH1A1NPC1RAB9AMAPTLMNA | |
| SCHEMBL29113343 | 0.81 | MAPT (0.53) | ALDH1A1NPC1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419610-B1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| EP-0419610-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS. | SCHERING AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| WO-1990011271-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1990-10-04 | — | — | WO | disclosed |