Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471741 | 0.78 | KCNH2 (0.35) | EHMT2MEN1KMT2AGAATHRB | |
| SCHEMBL8421437 | 0.77 | PPARG (0.42) | EHMT2MEN1KMT2AGAATHRB | |
| SCHEMBL8472107 | 0.76 | EHMT2 (0.34) | EHMT2MEN1KMT2AGAATHRB | |
| Hydrochloric Acid SCHEMBL8505852 | 0.76 | PPARG (0.43) | EHMT2MEN1KMT2AGAATHRB | |
| SCHEMBL8472016 | 0.76 | PDE4A (0.36) | EHMT2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3627524 | 0.75 | EHMT2 (0.45) | EHMT2MEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL9631715 | 0.75 | EHMT2 (0.45) | EHMT2MEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL7498416 | 0.75 | EHMT2 (0.45) | EHMT2MEN1KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL8576585 | 0.73 | MEN1 (0.36) | EHMT2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13294875 | 0.73 | EHMT2 (0.50) | EHMT2MEN1KMT2AMAPTELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555249-A1 | THIAZOLIDINEDIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| US-4725610-A | TREATMENT OF HYPERLIPEMIA AND DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |