Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526816 | 1.00 | KMT2A (0.44) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL2541499 | 0.91 | HDAC3 (0.38) | MAPTGAANPSR1LMNACYP3A4 | |
| SCHEMBL9526858 | 0.91 | HDAC3 (0.38) | MAPTGAANPSR1LMNACYP3A4 | |
| SCHEMBL2535653 | 0.88 | MAPT (0.38) | MAPTGAALMNACYP3A4HDAC3 | |
| SCHEMBL10551133 | 0.85 | MAPT (0.39) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL10551124 | 0.85 | MAPT (0.39) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL11139117 | 0.85 | KMT2A (0.52) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL11132942 | 0.85 | KMT2A (0.52) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL11140064 | 0.84 | KMT2A (0.50) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL11067485 | 0.84 | KMT2A (0.50) | KMT2AMEN1MAPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249170-B1 | CEPHEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4921851-A | Cephem compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0249170-A2 | Cephem compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-16 | — | — | EP | disclosed |