Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527529 | 0.95 | MAPT (0.40) | MAPTMAP3K14MEN1KMT2A | |
| SCHEMBL5398064 | 0.92 | MAP3K14 (0.36) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL9617095 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL18068311 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL12967711 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL15202859 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL17988729 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL2545200 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL17329444 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A | |
| SCHEMBL16664281 | 0.81 | MEN1 (0.34) | MAPTALDH1A1MAP3K14MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |
| US-4892943-A | ANTIPSYCHOTIC, ANXIOLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0220873-A1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-06 | — | — | EP | disclosed |