Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049503 | 0.88 | EPHX1 (0.58) | EPHX1HIF1AALDH1A1KMT2A | |
| SCHEMBL1007488 | 0.79 | EPHX1 (0.48) | EPHX1HIF1AALDH1A1NPC1RAB9A | |
| SCHEMBL10453742 | 0.79 | EPHX1 (0.52) | EPHX1HIF1AALDH1A1TSHR | |
| SCHEMBL28215461 | 0.77 | EPHX1 (0.48) | EPHX1HIF1AALDH1A1 | |
| SCHEMBL11161236 | 0.76 | EPHX1 (0.48) | EPHX1HIF1AALDH1A1MEN1KMT2A | |
| SCHEMBL29034357 | 0.75 | EPHX1 (0.44) | EPHX1HIF1AALDH1A1KMT2A | |
| SCHEMBL3278282 | 0.75 | HIF1A (0.44) | EPHX1HIF1AALDH1A1HRH3NPC1 | |
| Dicyclohexylcarbodiimide SCHEMBL7062217 | 0.75 | EPHX1 (0.52) | EPHX1HIF1AALDH1A1NPC1RAB9A | |
| SCHEMBL16946897 | 0.73 | POLB (0.43) | EPHX1HIF1ANOS1MEN1KMT2A | |
| Dicyclohexylcarbodiimide SCHEMBL28535893 | 0.69 | EPHX1 (0.94) | EPHX1HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |