Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 11/20 | 0.43 |
| ▸ | GYS1 | P13807 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529679 | 1.00 | DRD1 (0.43) | DRD1GYS1DRD5DRD2CYP2D6 | |
| SCHEMBL9532731 | 0.89 | DRD1 (0.40) | DRD1GYS1DRD5DRD2CYP2D6 | |
| SCHEMBL9771996 | 0.89 | DRD1 (0.40) | DRD1GYS1DRD5DRD2CYP2D6 | |
| SCHEMBL9528620 | 0.86 | DRD1 (0.36) | DRD1GYS1DRD5DRD2CYP2D6 | |
| SCHEMBL9530940 | 0.86 | DRD1 (0.36) | DRD1GYS1DRD5DRD2CYP2D6 | |
| SCHEMBL9529250 | 0.82 | DRD1 (0.44) | DRD1DRD5DRD2CYP2D6CYP1A2 | |
| SCHEMBL9772024 | 0.81 | DRD1 (0.40) | DRD1DRD5DRD2CYP2D6CYP1A2 | |
| SCHEMBL9529247 | 0.80 | DRD1 (0.42) | DRD1DRD5DRD2CYP2D6CYP1A2 | |
| SCHEMBL8911123 | 0.80 | DRD1 (0.55) | DRD1DRD5DRD2CYP2D6CYP1A2 | |
| SCHEMBL9531885 | 0.79 | DRD1 (0.42) | DRD1DRD5DRD2CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331130-B1 | CARBAMIC ACID ESTER OF SUBSTITUTED 7-HYDROXY-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES | NOVO NORDISK A/S (DK) | 1993-09-29 | — | — | EP | disclosed |
| US-5017571-A | Prodrugs, mental disorders | NOVO NORDISK A/S (DK) | 1991-05-21 | — | — | US | disclosed |
| EP-0331130-A1 | Carbamic acid ester of substituted 7-hydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines | NOVO NORDISK A/S (DK) | 1989-09-06 | — | — | EP | disclosed |