Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.81 |
| ▸ | THRB | P10828 | 8/20 | 0.81 |
| ▸ | BLM | P54132 | 7/20 | 0.81 |
| ▸ | RECQL | P46063 | 6/20 | 0.81 |
| ▸ | TOP2A | P11388 | 5/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.81 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.81 |
| ▸ | HTT | P42858 | 4/20 | 0.81 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.81 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.81 |
| ▸ | FYN | P06241 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22970091 | 1.00 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| Hydrochloric Acid SCHEMBL7518177 | 0.99 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL29001099 | 0.95 | MEN1 (0.81) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL43830 | 0.94 | MEN1 (0.83) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL13154315 | 0.94 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL20548043 | 0.94 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL17705921 | 0.94 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL22970097 | 0.94 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL111629 | 0.94 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL13181351 | 0.94 | MEN1 (0.82) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365024-A | Compounds, compositions and methods for preventing metastasis of cancer cells | AKEBIA THERAPEUTICS INC | 2012-02-29 | — | — | CN | claimed |
| US-6740333-B2 | MAY FURTHER COMPRISE A PLURALITY OF OPEN CELLS AT LEAST PARTLY SEPARATED FROM ONE ANOTHER BY AN INTERPENETRATING MATRIX COMPRISING AT LEAST ONE BIOCOMPATIBLE POLYMER IN BRANCHED OR CROSSLINKED FORM; NON-BIODEGRADABLE | ANESTIC APS (DK) | 2004-05-25 | — | — | US | claimed |
| CN-118359610-A | MENIN-MLL interaction inhibitors | 生命医药有限责任公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-109952309-B | Constitutive active cytokine receptors for cell therapy | 贝勒医学院 | 2024-06-07 | — | — | CN | disclosed |
| CN-110199018-B | Chimeric poxvirus compositions and uses thereof | 希望之城 | 2024-06-07 | — | — | CN | disclosed |
| CN-108472258-B | Formulations/compositions comprising BTK inhibitors | 詹森药业有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-112689528-B | Pyrimidinyl-heteroaryloxy-naphthyl compounds and methods of use | 基因泰克公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117999363-A | Compositions and methods for cell-free DNA epigenetic gastrointestinal cancer detection and treatment | 希望之城 | 2024-05-07 | — | — | CN | disclosed |
| CN-114341159-B | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117886943-A | Anti-renalase antibodies for the treatment and prevention of diseases and conditions | 耶鲁大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-113149983-B | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2024-03-29 | — | — | CN | disclosed |
| US-6063911-A | ANTITUMOR AGENT OF AT LEAST ONE ENDOTHELIN ANTAGONIST WITH A HIGH MOLECULAR WEIGHT POLY-BETA-1->4-N-ACETYLGLUCOSAMINE POLYSACCHARIDE MATRIX; ANTIPROLIFERATIVE/ANTICARCINOGENIC/ ANTIMETASTASIS AGENTS | MARINE POLYMER TECHNOLOGIES, INC. (US) | 2000-05-16 | — | — | US | disclosed |
| US-5858350-A | CHITIN, CHITOSAN | MARINE POLYMER TECHNOLOGIES (US) | 1999-01-12 | — | — | US | disclosed |
| US-5846952-A | Methods and compositions for poly-β-1-4-N-acetylglucosamine drug delivery | MARINE POLYMER TECHNOLOGIES, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998046286-A1 | BIODEGRADABLE COMPOUNDS, COMPOSITIONS, ARTICLES AND METHODS FOR MAKING AND USING THE SAME | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1998-10-22 | — | — | WO | disclosed |
| CN-1184123-A | Organic optical component | MITSUI TOATSU CHEMICALS (JP) | 1998-06-10 | — | — | CN | disclosed |
| US-5686115-A | Poly-β-1→4-N-acetylucosamine copolymer composition with collagen | MARINE POLYMER TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5635493-A | ADMINISTERING ENCAPSULATED ANTITUMOR DRUG | MARINE POLYMER TECHNOLOGIES, INC. (US) | 1997-06-03 | — | — | US | disclosed |
| US-5624679-A | REDUCTION OF POST-SURGICAL ADHESIONS | MARINE POLYMER TECHNOLOGIES, INC. (US) | 1997-04-29 | — | — | US | disclosed |
| WO-1996039122-A1 | POLY-β-1→4-N-ACETYLGLUCOSAMINE | MARINE POLYMER TECHNOLOGIES, INC. (US) | 1996-12-12 | — | — | WO | disclosed |