Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.73 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | AKT2 | P31751 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531164 | 1.00 | HTR2A (1.00) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| SCHEMBL9533613 | 1.00 | HTR2A (1.00) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| SCHEMBL149259 | 0.85 | HTR2A (1.00) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| Bromide SCHEMBL6737914 | 0.83 | HTR2A (0.94) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| Water SCHEMBL28365853 | 0.83 | HTR2A (0.94) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| Hydrochloric Acid SCHEMBL8550503 | 0.83 | HTR2A (0.94) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| SCHEMBL1034162 | 0.82 | HTR2A (0.68) | HTR2ATAAR1CHRNB2CHRNA4AKT2 | |
| SCHEMBL3902718 | 0.81 | HTR2A (0.68) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| SCHEMBL38652540 | 0.80 | HTR2A (0.89) | HTR2ATAAR1CHRNB2CHRNA4HRH1 | |
| Hydroxyamine SCHEMBL4363096 | 0.80 | HTR2A (0.89) | HTR2ATAAR1CHRNB2CHRNA4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573548-A1 | NEUROPROTECTANT AGENTS. | AMERICAN HOME PROD (US) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992014813-A1 | NEUROPROTECTANT AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |