Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191323 | 0.83 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30884946 | 0.83 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30884942 | 0.83 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30884947 | 0.83 | CA1 (0.50) | CA1CA2CA12CA7CA9 | |
| SCHEMBL2385010 | 0.82 | TDP1 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30884941 | 0.82 | KMT2A (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL16389692 | 0.80 | CA1 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL25330864 | 0.79 | CA1 (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31325033 | 0.79 | CA1 (0.45) | CA1CA2CA12CA7CA9 | |
| SCHEMBL87450 | 0.77 | CA1 (0.83) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394476-B1 | NOVEL 1,3,4-THIADIAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5106859-A | CERTAIN 1,3,4-THIADIAZOLE DERIVATIVES AND ANTI-ULCER AGENT COMPRISING SAID DERIVATIVES AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0394476-A1 | NOVEL 1,3,4-THIADIAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1990-10-31 | — | — | EP | disclosed |