SCHEMBL9529264

SCHEMBL9529264

OP(O)On1cnc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
HTT P42858 3/20 0.44
FGFR1 P11362 3/20 0.43
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
STAT6 P42226 1/20 0.42
POLB P06746 1/20 0.41
TNF P01375 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KMT2A Q03164 2/20 0.39
AGER Q15109 1/20 0.39
MEN1 O00255 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1293053 0.79 TDP1 (0.52) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL491202 0.76 HTT (0.50) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL3968932 0.76 TDP1 (0.48) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL6392854 0.76 EGLN3 (0.46) TDP1HTTFGFR1SMN1; SMN2EGLN3
SCHEMBL8901472 0.76 EGLN3 (0.46) TDP1HTTFGFR1SMN1; SMN2EGLN3
SCHEMBL4180919 0.74 TDP1 (0.47) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL9378132 0.74 EGLN3 (0.49) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL24054627 0.73 HTT (0.47) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL160156 0.73 TDP1 (0.46) TDP1HTTFGFR1LMNASMN1; SMN2
SCHEMBL1884001 0.73 KMT2A (0.46) TDP1HTTFGFR1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0286478-B1 PHOSPHOROUS-ACID SALTS, THEIR COMMPOSITIONS AND THEIR USE AS FIRE-PROOFING AGENTS ELF ATOCHEM S.A. (FR) 1993-03-10 EP claimed