⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285987 | 0.75 | — | — | |
| SCHEMBL1359211 | 0.75 | — | — | |
| SCHEMBL830552 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL9127358 | 0.73 | — | — | |
| SCHEMBL10414526 | 0.71 | — | — | |
| SCHEMBL13116075 | 0.71 | HPGD (0.40) | — | |
| SCHEMBL17633086 | 0.67 | HPGD (0.36) | — | |
| SCHEMBL18140092 | 0.67 | TDP1 (0.36) | — | |
| SCHEMBL27845738 | 0.67 | — | — | |
| SCHEMBL28886836 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4861726-A | Method of thioacylation peptide sequencing with acylation of thiazoloinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-08-29 | — | — | US | claimed |
| US-20250327811-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING DITHIOESTER AND THIOCARBAMOYL AMINO ACID REACTIVE GROUPS | GLYPHIC BIOTECHNOLOGIES, INC. | 2025-10-23 | — | — | US | disclosed |
| EP-4619761-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING DITHIOESTER AND THIOCARBAMOYL AMINO ACID REACTIVE GROUPS | Glyphic Biotechnologies, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107755-A1 | SINGLE-MOLECULE PEPTIDE SEQUENCING USING DITHIOESTER AND THIOCARBAMOYL AMINO ACID REACTIVE GROUPS | GLYPHIC BIOTECHNOLOGIES, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| EP-0252474-B1 | HYDRAZINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0397813-A1 | METHOD FOR SEQUENCING PEPTIDES OR PROTEINS | Novabiochem AG (CH) | 1990-11-22 | — | — | EP | disclosed |
| WO-1990005192-A1 | METHOD FOR SEQUENCING PEPTIDES OR PROTEINS | PHARMACIA AB (SE) | 1990-05-17 | — | — | WO | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| WO-1989008835-A1 | THIOACYLATION PEPTIDE SEQUENCING WITH ACYLATION OF THIAZOLINES | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-21 | — | — | WO | disclosed |
| US-4863870-A | Method of thioacylation peptide sequencing with alcoholysis of thiazolinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4861726-A | Method of thioacylation peptide sequencing with acylation of thiazoloinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| US-4518682-A | CONTAINING COMPOUND WHICH GIVES FOGGING EFFECT | FUJI PHOTO FILM CO., LTD. (JP) | 1985-05-21 | — | — | US | disclosed |
| US-4153416-A | Process and apparatus for pulse labelling protein material in the Edman degradation process | HEWLETT-PACKARD COMPANY, 3000 HANOVER ST., PALO ALTO, CA A CORP. OF CA | 1979-05-08 | — | — | US | disclosed |