Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207126 | 0.87 | MAOB (0.47) | SERPINE1MAOBSCN8ASCN10ANPC1 | |
| SCHEMBL9202545 | 0.86 | CA1 (0.47) | SERPINE1MAOBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9202456 | 0.86 | P2RX1 (0.48) | SERPINE1MAOB | |
| SCHEMBL9201665 | 0.85 | MAOB (0.58) | TRPV1SERPINE1MAOBEPHX2KMT2A | |
| SCHEMBL8441905 | 0.82 | P2RX1 (0.54) | MAOBMEN1KMT2ANPC1 | |
| SCHEMBL10679004 | 0.80 | VKORC1 (0.52) | TRPV1SERPINE1MAOBMEN1KMT2A | |
| SCHEMBL9208790 | 0.80 | KCNQ3 (0.56) | — | |
| SCHEMBL9205476 | 0.79 | MAPT (0.52) | MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8441752 | 0.79 | VKORC1 (0.58) | MAOBMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL10676841 | 0.78 | TLR8 (0.56) | SERPINE1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550493-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1993-07-14 | — | — | EP | claimed |
| WO-1992006083-A1 | ANTHELMINTIC AND ANTICOCCIDAL 3-CARBAMOYL-4-HYDROXYCOUMARINS, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-04-16 | — | — | WO | claimed |