Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529835 | 1.00 | MEN1 (0.73) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL7103409 | 0.85 | KMT2A (0.54) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL26123831 | 0.84 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4348625 | 0.84 | SMN1; SMN2 (0.71) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11697622 | 0.83 | NPSR1 (1.00) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL6565598 | 0.82 | SMN1; SMN2 (0.68) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL28756963 | 0.80 | SMN1; SMN2 (0.83) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL12313913 | 0.80 | SMN1; SMN2 (0.70) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11845603 | 0.80 | SMN1; SMN2 (1.00) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10143959 | 0.78 | SMN1; SMN2 (0.72) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |