Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.71 |
| ▸ | CA2 | P00918 | 12/20 | 0.71 |
| ▸ | CA4 | P22748 | 12/20 | 0.71 |
| ▸ | CA6 | P23280 | 12/20 | 0.71 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.50 |
| ▸ | CDK1 | P06493 | 3/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | MDH2 | P40926 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298597 | 0.82 | CA1 (1.00) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL29370925 | 0.82 | CA1 (1.00) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL12382594 | 0.82 | CA1 (0.69) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL2299152 | 0.82 | CA1 (0.71) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL2294178 | 0.78 | CA1 (0.73) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL22250400 | 0.75 | CA1 (0.43) | CA1CA2CA4CA6ACHE | |
| SCHEMBL28217847 | 0.74 | CA1 (0.47) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL9526530 | 0.74 | CCNB2 (0.63) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL19353002 | 0.73 | CA1 (0.69) | CA1CA2CA4CA6CCNB2 | |
| SCHEMBL15759621 | 0.73 | CDK1 (0.72) | CA1CA2CA4CA6CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |