SCHEMBL9531144

SCHEMBL9531144

CC(C)C(=O)Cl.CCCC(=O)Cl

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.74
ALDH1A1 P00352 3/20 0.52
TP53 P04637 1/20 0.52
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
HDAC3 O15379 4/20 0.39
HDAC1 Q13547 4/20 0.39
HDAC2 Q92769 4/20 0.39
HDAC8 Q9BY41 4/20 0.39
FFAR3 O14843 3/20 0.39
HDAC6 Q9UBN7 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
CTSD P07339 1/20 0.33
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
FAAH O00519 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6936094 0.86
SCHEMBL2819 0.86
Fluoride SCHEMBL27290847 0.83
Water SCHEMBL28860102 0.83 TSHR (0.93) TSHRALDH1A1TP53CES2CES1
Water SCHEMBL27399407 0.83
SCHEMBL28389065 0.83
Iodide SCHEMBL27032697 0.83
SCHEMBL5918593 0.83
SCHEMBL8196027 0.83
Hydrochloric Acid SCHEMBL27280754 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0361510-B1 Antitumor substance, process for preparing the same, and anticancer agent containing the same MEIJI SEIKA KAISHA (JP) 1993-12-01 EP disclosed
US-5098968-A Coating reactors with the reaction product of tannins with acid halide SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-03-24 US disclosed
EP-0397009-A2 Method of preventing polymer scale deposition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-11-14 EP disclosed
EP-0361510-A2 Antitumor substance, process for preparing the same, and anticancer agent containing the same MEIJI SEIKA KAISHA LTD. (JP) 1990-04-04 EP disclosed