Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10427550 | 0.92 | SRD5A2 (0.40) | SRD5A2CYP3A4 | |
| SCHEMBL17621065 | 0.87 | SRD5A2 (0.49) | TP53LMNAMAPTTSHRRAB9A | |
| SCHEMBL17621034 | 0.82 | TP53 (0.52) | TP53LMNAMAPTTSHRRAB9A | |
| SCHEMBL9532887 | 0.80 | TP53 (0.42) | TP53LMNAMAPTTSHRRAB9A | |
| SCHEMBL11222988 | 0.73 | HSD17B10 (0.56) | TP53LMNAMAPTTSHRRAB9A | |
| SCHEMBL28347137 | 0.72 | MGAM (0.54) | TP53LMNAMAPTTSHRRAB9A | |
| SCHEMBL17621078 | 0.70 | TP53 (0.43) | TP53LMNAMAPTTSHRRAB9A | |
| SCHEMBL29660211 | 0.70 | TP53 (0.43) | TP53LMNAMAPTTSHRRAB9A | |
| SCHEMBL8272766 | 0.69 | MEN1 (0.54) | LMNAMAPTRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL20518827 | 0.69 | IRAK4 (0.53) | TP53LMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313458-B1 | IMIDAZO(2,1-B)BENZOTHIAZOLES AND THEIR ACID ADDITION SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-08-11 | — | — | EP | claimed |
| US-4895863-A | MEMORY DISORDERS | ROUSSEL UCLAF (FR) | 1990-01-23 | — | — | US | claimed |
| US-4895863-A | MEMORY DISORDERS | ROUSSEL UCLAF (FR) | 1990-01-23 | — | — | US | disclosed |