SCHEMBL9532206

SCHEMBL9532206

O=C1CC(c2cc(O)ccc2O)=NN1c1ccc(Br)cc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 18/20 0.54
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9536258 0.87 MAOB (0.52) MAOBGAA
SCHEMBL5455130 0.85 MAOB (0.53) MAOBGAA
SCHEMBL9537036 0.84 MAOB (0.58) MAOBGAA
SCHEMBL9534068 0.84 MAOB (0.62) MAOBGAA
SCHEMBL9531614 0.83 MAOB (0.49) MAOB
SCHEMBL10381192 0.78 MAOB (0.59) MAOBGAA
SCHEMBL9535278 0.75 MAOB (0.57) MAOBGAA
SCHEMBL6521596 0.75 GAA (0.66) GAA
SCHEMBL9533173 0.74 MAOB (0.65) MAOBGAA
SCHEMBL10381178 0.72 MAOB (0.55) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539372-A1 THERAPEUTIC AGENTS The Boots Company PLC (GB) 1993-05-05 EP disclosed
WO-1991011448-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1991-08-08 WO disclosed