Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.47 |
| ▸ | CDC25B | P30305 | 5/20 | 0.47 |
| ▸ | ACP1 | P24666 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15798299 | 0.98 | PTPN1 (0.46) | PTPN1CDC25BACP1EPHX2LMNA | |
| SCHEMBL21810871 | 0.93 | PTPN1 (0.50) | PTPN1CDC25BACP1LMNAHSD17B10 | |
| SCHEMBL15811725 | 0.87 | PTPN1 (0.45) | PTPN1CDC25BACP1 | |
| SCHEMBL1549875 | 0.75 | PTPN1 (0.41) | PTPN1CDC25BACP1LMNAHSD17B10 | |
| SCHEMBL9190067 | 0.72 | PTPN1 (0.46) | PTPN1CDC25BACP1LMNAHSD17B10 | |
| SCHEMBL1356857 | 0.72 | PTPN1 (0.62) | PTPN1CDC25BACP1LMNAHSD17B10 | |
| SCHEMBL17748526 | 0.71 | PTPN1 (0.56) | PTPN1CDC25BACP1LMNARAB9A | |
| SCHEMBL20351495 | 0.71 | PTPN1 (0.56) | PTPN1CDC25BACP1LMNARAB9A | |
| SCHEMBL14194487 | 0.71 | PTPN1 (0.57) | PTPN1CDC25BACP1LMNAHSD17B10 | |
| SCHEMBL7114676 | 0.69 | PTPN1 (0.74) | PTPN1CDC25BACP1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |