SCHEMBL9532841

SCHEMBL9532841

N#CC(O)CCCCCCOC1CCCCO1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4C Q9H3R0 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
CHEK1 O14757 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26064114 0.83 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL15028143 0.83 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL26666204 0.83 MEN1 (0.50) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL10688436 0.81 MEN1 (0.48) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL11259327 0.80 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL15236500 0.80 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL15236501 0.80 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL15236494 0.80 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL15236498 0.80 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL15236522 0.80 MEN1 (0.47) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560794-A1 SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. IAF BIOCHEM INT (CA) 1993-09-22 EP claimed
EP-0560794-A1 SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. IAF BIOCHEM INT (CA) 1993-09-22 EP disclosed
EP-0251827-B1 NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE Sankyo Company Limited (JP) 1993-09-15 EP disclosed
US-4891363-A PLATELET ACTIVATING FACTOR ANTAGONISTS SANKYO COMPANY LIMITED (JP) 1990-01-02 US disclosed
EP-0251827-A2 New cyclic ether derivatives, their preparation and their use Sankyo Company Limited (JP) 1988-01-07 EP disclosed