Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953299 | 1.00 | EBP (0.40) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL953019 | 0.88 | EBP (0.40) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL953021 | 0.88 | EBP (0.40) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL955063 | 0.83 | CHRM1 (0.42) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL955064 | 0.83 | CHRM1 (0.42) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL953879 | 0.82 | EBP (0.41) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL953880 | 0.82 | EBP (0.41) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL957522 | 0.82 | CHRM1 (0.41) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL957519 | 0.82 | CHRM1 (0.41) | EBPSIGMAR1LMNASMN1; SMN2DHCR7 | |
| SCHEMBL953898 | 0.81 | SMN1; SMN2 (0.46) | EBPSIGMAR1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796274-B2 | Piperazine derivatives and their use in controlling pests | SYNGENTA CROP PROTECTION LLC (US) | 2014-08-05 | — | — | US | disclosed |
| EP-1755396-B1 | PIPERAZIN DERIVATIVES AND THEIR USE IN CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-06-18 | — | — | EP | disclosed |
| US-20110003991-A1 | PIPERAZINE DERIVATIVES AND THEIR USE IN CONTROLLING PESTS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003991-A1 | PIPERAZINE DERIVATIVES AND THEIR USE IN CONTROLLING PESTS | CHRM1, CHRM5, PRMT5 | EBP 3189/4885SIGMAR1 160/4885LMNA 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.