Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534900 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2CYSLTR2CYSLTR1FPR2TLR8 | |
| SCHEMBL9533128 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2CYSLTR2CYSLTR1FPR2TLR8 | |
| SCHEMBL9534515 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2CYSLTR2CYSLTR1TLR8 | |
| SCHEMBL9536344 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2CYSLTR2CYSLTR1FPR2TLR8 | |
| SCHEMBL9538934 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2FPR2PLA2G4BTLR8 | |
| SCHEMBL9536637 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2CYSLTR2CYSLTR1FPR2TLR8 | |
| Acetic Acid SCHEMBL28952653 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2TLR8 | |
| Acetic Acid SCHEMBL29137536 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2TLR8 | |
| SCHEMBL9536020 | 0.70 | SMN1; SMN2 (0.47) | SMN1; SMN2CYSLTR2CYSLTR1FPR2PLA2G4B | |
| SCHEMBL4436250 | 0.69 | SMN1; SMN2 (0.50) | SMN1; SMN2FPR2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |