Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 9/20 | 0.52 |
| ▸ | PRCP | P42785 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bepotastine SCHEMBL5151702 | 0.94 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL30200949 | 0.94 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL726880 | 0.94 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL29440897 | 0.94 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL29459 | 0.94 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL2808049 | 0.93 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL2806225 | 0.93 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL2807641 | 0.93 | BCHE (0.55) | BCHEDRD2FAAH | |
| Bepotastine SCHEMBL2803678 | 0.93 | BCHE (0.55) | BCHEDRD2FAAH | |
| SCHEMBL28391952 | 0.92 | BCHE (0.56) | BCHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929618-A | ANTIALLERGENS, ANTIHISTAMINES | UBE INDUSTRIES, LTD. (JP) | 1990-05-29 | — | — | US | claimed |
| JP-2025465-A | — | — | None | — | — | JP | disclosed |
| EP-0335586-B1 | PIPERIDINE & PIPERAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| EP-0525129-A4 | SUBSTITUTED BENZIMIDAZOLES | — | 1993-03-24 | — | — | EP | disclosed |
| EP-0525129-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4929618-A | ANTIALLERGENS, ANTIHISTAMINES | UBE INDUSTRIES, LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| JP-H0225465-A | PIPERIDINE DERIVATIVE, PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME DERIVATIVE | UBE IND LTD | 1990-01-26 | — | — | JP | disclosed |
| EP-0335586-A1 | Piperidine & piperazine derivatives, process for preparing the same and pharmaceutical compositions containing the same | UBE INDUSTRIES, LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |