⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144439 | 0.82 | GRIN2D (0.32) | — | |
| SCHEMBL450187 | 0.74 | — | — | |
| SCHEMBL5858921 | 0.67 | — | — | |
| SCHEMBL1811164 | 0.67 | — | — | |
| SCHEMBL15248832 | 0.64 | GRIN2D (0.39) | — | |
| SCHEMBL19542912 | 0.64 | GRIN2D (0.39) | — | |
| SCHEMBL1106433 | 0.64 | — | — | |
| SCHEMBL6663337 | 0.64 | GRIN2D (0.39) | — | |
| SCHEMBL278410 | 0.64 | GRIN2D (0.39) | — | |
| SCHEMBL1394430 | 0.62 | CYP1A2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |