Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346936 | 0.82 | CYP2D6 (0.36) | KMT2ACYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL9531503 | 0.78 | KMT2A (0.31) | KMT2ACYP2D6 | |
| Nitric Acid SCHEMBL27774290 | 0.77 | KDM4E (0.46) | KMT2ACYP2D6TSHRCYP2C19HIF1A | |
| Nitric Acid SCHEMBL28391259 | 0.72 | CYP2C19 (0.38) | KMT2ACYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL63265 | 0.71 | — | — | |
| SCHEMBL23863190 | 0.69 | — | — | |
| SCHEMBL27867007 | 0.69 | — | — | |
| SCHEMBL1490968 | 0.69 | — | — | |
| SCHEMBL3607267 | 0.67 | — | — | |
| SCHEMBL7555585 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325513-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-2-METHYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1993-04-07 | — | — | EP | disclosed |
| EP-0324692-B1 | PROCESS FOR THE PREPARATION OF HYDROXYALKYLATING AGENTS, THE AGENTS AS PREPARED AND THEIR USE | RHONE-POULENC SANTE (FR) | 1992-11-25 | — | — | EP | disclosed |
| EP-0324691-B1 | PROCESS FOR THE PREPARATION OF 1-HYDROXYALKYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1991-12-27 | — | — | EP | disclosed |
| EP-0325513-A1 | Process for the preparation of 1-hydroxyalkyl-2-methyl-5-nitro-imidazoles | RHONE-POULENC SANTE (FR) | 1989-07-26 | — | — | EP | disclosed |
| EP-0324692-A1 | Process for the preparation of hydroxyalkylating agents, the agents as prepared and their use | RHONE-POULENC SANTE (FR) | 1989-07-19 | — | — | EP | disclosed |
| EP-0324691-A1 | Process for the preparation of 1-hydroxyalkyl-5-nitro-imidazoles | RHONE-POULENC SANTE (FR) | 1989-07-19 | — | — | EP | disclosed |