Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10381797 | 0.92 | MAOB (0.49) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9533087 | 0.90 | MAOB (0.57) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9537036 | 0.88 | MAOB (0.58) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL10381192 | 0.86 | MAOB (0.59) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9535278 | 0.85 | MAOB (0.57) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9536258 | 0.84 | MAOB (0.52) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9533173 | 0.82 | MAOB (0.65) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL10381178 | 0.81 | MAOB (0.55) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL9534595 | 0.81 | MAOB (0.59) | MAOBMEN1KMT2AMAPTTDP1 | |
| SCHEMBL10381181 | 0.80 | MAOB (0.58) | MAOBMEN1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1991011448-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-08-08 | — | — | WO | disclosed |
| WO-1990001481-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1990-02-22 | — | — | WO | disclosed |
| EP-0354693-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1990-02-14 | — | — | EP | disclosed |