Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12268199 | 1.00 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL12317735 | 1.00 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL15059297 | 1.00 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL15382010 | 1.00 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL9532224 | 1.00 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL8398424 | 1.00 | PPM1B (0.55) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL392329 | 0.91 | PPM1B (0.59) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL392595 | 0.91 | PPM1B (0.59) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL4387586 | 0.91 | PPM1B (0.59) | PPM1BPTPN1PPP1CCALDH1A1KMT2A | |
| SCHEMBL392330 | 0.91 | PPM1B (0.59) | PPM1BPTPN1PPP1CCALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2256650-A | — | — | None | — | — | JP | disclosed |
| EP-0352083-B1 | Alkenyltetrazole derivatives, their preparation and use | SHIONOGI & CO (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0373949-B1 | MONO ESTERS OF DICARBOXYLIC ACIDS, THEIR PREPARATION AND USE | SHIONOGI & CO (JP) | 1993-08-25 | — | — | EP | disclosed |
| JP-H02256650-A | DICARBOXYLIC ACID MONOESTER AND PRODUCTION THEREOF | SHIONOGI & CO LTD | 1990-10-17 | — | — | JP | disclosed |
| EP-0384747-A1 | Pharmaceutical or veterinary preparations of substituted hexenoic acid derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4916231-A | THROMBOXANE A2 RECPTOR ANTAGONISTS | SHIONOGI & CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0352083-A2 | Alkenyltetrazole derivatives, their preparation and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |