Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641754 | 0.87 | KDM4E (0.47) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL9531833 | 0.87 | KDM4E (0.45) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL10642759 | 0.86 | KDM4E (0.41) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL9532638 | 0.85 | KDM4E (0.43) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL10639070 | 0.83 | KDM4E (0.39) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL10639179 | 0.83 | KDM4E (0.41) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL9530663 | 0.83 | TSHR (0.40) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL9531921 | 0.83 | AKT1 (0.36) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL9531337 | 0.82 | KDM4E (0.40) | ALDH1A1KDM4EGAAHPGDCASP1 | |
| SCHEMBL9533798 | 0.82 | PPARG (0.41) | F2F10ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |