Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 13/20 | 0.47 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24021919 | 0.84 | HPRT1 (0.47) | HPRT1PNP | |
| SCHEMBL1993930 | 0.71 | HPRT1 (0.63) | HPRT1PNPLMNA | |
| SCHEMBL9533319 | 0.71 | HPRT1 (0.64) | HPRT1PNP | |
| SCHEMBL7684892 | 0.70 | HPRT1 (0.67) | HPRT1PNP | |
| SCHEMBL1992701 | 0.70 | HPRT1 (0.54) | HPRT1PNPALDH1A1 | |
| SCHEMBL16276016 | 0.70 | HPRT1 (0.50) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL20782416 | 0.69 | HPRT1 (0.65) | HPRT1PNP | |
| SCHEMBL7396872 | 0.69 | HPRT1 (0.46) | HPRT1PNP | |
| SCHEMBL11243638 | 0.69 | HPRT1 (0.49) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL21385661 | 0.68 | HPRT1 (0.55) | HPRT1PNPALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522082-A4 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | — | 1993-06-09 | — | — | EP | disclosed |
| EP-0522082-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE. | GLASKY ALVIN J (US) | 1993-01-13 | — | — | EP | disclosed |