Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824375 | 0.80 | NPC1 (0.69) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL29531707 | 0.80 | NPC1 (0.69) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL13700911 | 0.78 | ELANE (0.63) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL6981618 | 0.77 | NPC1 (0.54) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL31575855 | 0.75 | NPC1 (0.46) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| 2-Phenylbenzo[D]Oxazole SCHEMBL31275269 | 0.73 | NPC1 (0.70) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL171055 | 0.72 | TOP2A (0.62) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL21674121 | 0.72 | NPC1 (0.63) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL31170 | 0.72 | NPC1 (0.81) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| Anthracene SCHEMBL29003509 | 0.72 | NPC1 (0.66) | NPC1ALDH1A1RAB9AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102977238-A | Bi-dentate titanium based olefin polymerization catalyst, as well as preparation method and application thereof | UNIV FUDAN | 2013-03-20 | — | — | CN | claimed |
| CN-102977238-B | Bi-dentate titanium based olefin polymerization catalyst, as well as preparation method and application thereof | UNIV FUDAN | 2015-04-22 | — | — | CN | disclosed |
| CN-103333131-A | Preparation method of 2-aminobenzoxazole compound | SUZHOU OST ADVANCED MATERIALS CO LTD | 2013-10-02 | — | — | CN | disclosed |
| CN-102977238-A | Bi-dentate titanium based olefin polymerization catalyst, as well as preparation method and application thereof | UNIV FUDAN | 2013-03-20 | — | — | CN | disclosed |
| US-5248782-A | Fluorescent dyes | MOLECULAR PROBES, INC. (US) | 1993-09-28 | — | — | US | disclosed |