Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 9/20 | 0.80 |
| ▸ | PRKDC | P78527 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.53 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.53 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327239 | 0.89 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL7317064 | 0.81 | PRKDC (0.68) | P2RY12PRKDCKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL910153 | 0.79 | PRKDC (0.84) | P2RY12PRKDCKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7328250 | 0.77 | PRKDC (0.68) | P2RY12PRKDCKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8799719 | 0.77 | P2RY12 (0.79) | P2RY12PRKDC | |
| SCHEMBL8882123 | 0.77 | P2RY12 (0.75) | P2RY12PRKDCPIK3CA | |
| SCHEMBL3542889 | 0.76 | PRKDC (1.00) | P2RY12PRKDCKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7326771 | 0.76 | P2RY12 (0.82) | P2RY12PRKDCKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9537386 | 0.76 | P2RY12 (0.60) | P2RY12PRKDC | |
| SCHEMBL4415734 | 0.76 | PRKDC (0.72) | PRKDCKDM4EALDH1A1SMN1; SMN2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019707-A2 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | claimed |
| EP-0525123-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES. | UPJOHN CO (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991019707-A2 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |