Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538547 | 0.93 | MEN1 (0.49) | MEN1KMT2ATSHRPDE3ATAS1R3 | |
| SCHEMBL9537021 | 0.86 | MEN1 (0.54) | MEN1KMT2ATSHRPDE3ATAS1R3 | |
| SCHEMBL9537005 | 0.86 | MEN1 (0.54) | MEN1KMT2ATSHRPDE3ATAS1R3 | |
| SCHEMBL9537009 | 0.86 | MEN1 (0.54) | MEN1KMT2ATSHRPDE3ATAS1R3 | |
| SCHEMBL6378699 | 0.81 | MEN1 (0.58) | MEN1KMT2ATSHRPDE3ATAS1R3 | |
| SCHEMBL6839422 | 0.79 | MEN1 (0.56) | MEN1KMT2ATSHRPDE3AALDH1A1 | |
| SCHEMBL9663096 | 0.78 | MEN1 (0.55) | MEN1KMT2ATSHRPDE3AALDH1A1 | |
| SCHEMBL9662616 | 0.78 | MEN1 (0.54) | MEN1KMT2ATSHRPDE3AALDH1A1 | |
| SCHEMBL9536237 | 0.77 | MEN1 (0.46) | MEN1KMT2ATSHRTAS1R3TAS1R1 | |
| SCHEMBL9536276 | 0.77 | MEN1 (0.46) | MEN1KMT2ATSHRTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006112-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-01 | — | — | WO | claimed |
| WO-1993006112-A1 | THERAPEUTIC NUCLEOSIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |