SCHEMBL9536273

SCHEMBL9536273

CC(Cl)(Cl)C1=NCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3189143 0.80
SCHEMBL719165 0.80 KCNN4 (0.47)
SCHEMBL1744025 0.80
SCHEMBL3461729 0.78 KCNN4 (0.45)
SCHEMBL9185274 0.76
SCHEMBL14152228 0.76
SCHEMBL5940421 0.76 KCNN4 (0.40)
SCHEMBL11210610 0.76 KCNN4 (0.40)
SCHEMBL20354230 0.73 KCNN4 (0.41)
SCHEMBL12923885 0.73 KCNN4 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4320069-A Oxazoline stabilized diphenylmethane diisocyanate-polymethylene polyphenyl isocyanate compositions ATLANTIC RICHFIELD COMPANY (US) 1982-03-16 US claimed
EP-0195126-B1 STAR-BRANCHED POLYAMIDES AND STAR-BRANCHED POLYAMINE DERIVATES THEREOF THE DOW CHEMICAL COMPANY (US) 1993-09-29 EP disclosed
US-4690985-A Star/comb-branched polyamine THE DOW CHEMICAL COMPANY (US) 1987-09-01 US disclosed
EP-0195126-A2 Star-branched polyamides and star-branched polyamine derivates thereof THE DOW CHEMICAL COMPANY (US) 1986-09-24 EP disclosed
US-4599400-A POLYOXAZOLINE THICKENERS THE DOW CHEMICAL COMPANY (US) 1986-07-08 US disclosed
US-4320069-A Oxazoline stabilized diphenylmethane diisocyanate-polymethylene polyphenyl isocyanate compositions ATLANTIC RICHFIELD COMPANY (US) 1982-03-16 US disclosed
US-3962235-A TERT-ALKYL-HYPOCHLORITES THE DOW CHEMICAL COMPANY (US) 1976-06-08 US disclosed