Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.46 |
| ▸ | RARB | P10826 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL29008938 | 0.71 | RARB (0.63) | TP53TSHRRARBKMT2AMEN1 | |
| SCHEMBL27943869 | 0.71 | CYSLTR2 (0.41) | TP53TSHRKMT2AMEN1MAPT | |
| SCHEMBL27963649 | 0.71 | CYSLTR2 (0.41) | TP53TSHRKMT2AMEN1MAPT | |
| SCHEMBL8133487 | 0.70 | TP53 (0.59) | TP53TSHRPLA2G4BRARBKMT2A | |
| SCHEMBL28349098 | 0.70 | TP53 (0.59) | TP53TSHRPLA2G4BRARBKMT2A | |
| SCHEMBL2255421 | 0.70 | TP53 (0.59) | TP53TSHRPLA2G4BRARBKMT2A | |
| SCHEMBL9513370 | 0.69 | TP53 (0.62) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL2183384 | 0.69 | TP53 (0.62) | TP53TSHRPLA2G4BRARBKMT2A | |
| SCHEMBL2181006 | 0.69 | TP53 (0.62) | TP53TSHRPLA2G4BRARBKMT2A | |
| SCHEMBL5915075 | 0.69 | TP53 (0.62) | TP53TSHRPLA2G4BRARBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |