Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 7/20 | 0.67 |
| ▸ | DHFR | P00374 | 2/20 | 0.53 |
| ▸ | ATIC | P31939 | 3/20 | 0.50 |
| ▸ | FPGS | Q05932 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487523 | 0.97 | GART (0.64) | GARTDHFRATICFPGS | |
| SCHEMBL9050048 | 0.95 | GART (0.61) | GARTDHFRATICFPGS | |
| Lometrexol SCHEMBL12022771 | 0.94 | GART (0.75) | GARTDHFRATICTYMS | |
| Lometrexol SCHEMBL9045915 | 0.94 | GART (0.75) | GARTDHFRATICTYMS | |
| SCHEMBL9536782 | 0.93 | GART (0.68) | GARTDHFRATICFPGS | |
| SCHEMBL7487728 | 0.92 | GART (0.62) | GARTDHFRATICFPGS | |
| SCHEMBL7488545 | 0.91 | GART (0.71) | GARTDHFRATICTYMS | |
| SCHEMBL7487513 | 0.91 | GART (0.71) | GARTDHFRATICTYMS | |
| SCHEMBL7487721 | 0.90 | GART (0.65) | GARTDHFRATIC | |
| SCHEMBL9218459 | 0.89 | GART (0.54) | GARTDHFRATICFPGSTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215063-B1 | PYRIDO (2,3-d )PYRIMIDIN DERIVATIVES | UNIV PRINCETON (US) | 1993-11-03 | — | — | EP | claimed |