Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537159 | 1.00 | DPP4 (0.41) | DPP4CA12CA1CA9DPP8 | |
| Hydrochloric Acid SCHEMBL9439468 | 0.98 | DPP4 (0.40) | DPP4CA12CA1CA9DPP8 | |
| Hydrochloric Acid SCHEMBL9439130 | 0.98 | DPP4 (0.40) | DPP4CA12CA1CA9DPP8 | |
| SCHEMBL19981632 | 0.94 | CA12 (0.45) | DPP4CA12CA1CA9DPP8 | |
| SCHEMBL19981940 | 0.86 | DPP4 (0.44) | DPP4CA12CA1CA9DPP8 | |
| SCHEMBL4155821 | 0.79 | CA1 (0.45) | CA12CA1CA9CA2MMP1 | |
| SCHEMBL946188 | 0.78 | CA12 (0.47) | CA12CA1CA9CA2MMP1 | |
| SCHEMBL22907546 | 0.78 | CA12 (0.47) | CA12CA1CA9CA2MMP1 | |
| SCHEMBL4152729 | 0.78 | CA12 (0.47) | CA12CA1CA9CA2MMP1 | |
| SCHEMBL4162400 | 0.78 | CA12 (0.47) | CA12CA1CA9CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480969-A4 | AMINO ACID ANALOG CCK ANTAGONISTS | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0480969-A1 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | disclosed |