Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TOP2A | P11388 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923354 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8925826 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8923363 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8923518 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8925713 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8925752 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8924285 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8925675 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8925784 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8926310 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559774-A1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | claimed |