Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634979 | 0.86 | PREP (0.48) | PREPNPC1RAB9AL3MBTL1 | |
| SCHEMBL10749955 | 0.83 | PREP (0.67) | PREPSPHK2L3MBTL1CTRB1 | |
| SCHEMBL10657139 | 0.83 | PREP (0.67) | PREPSPHK2L3MBTL1CTRB1 | |
| SCHEMBL8639478 | 0.81 | PREP (0.65) | PREPL3MBTL1CTRB1 | |
| SCHEMBL5763420 | 0.80 | NPC1 (0.53) | NPC1RAB9AL3MBTL1CTRB1 | |
| SCHEMBL809494 | 0.80 | SPHK2 (0.58) | PREPSPHK2NPC1RAB9AL3MBTL1 | |
| SCHEMBL4602602 | 0.80 | SPHK2 (0.58) | PREPSPHK2NPC1RAB9AL3MBTL1 | |
| SCHEMBL5267939 | 0.80 | SPHK2 (0.58) | PREPSPHK2NPC1RAB9AL3MBTL1 | |
| SCHEMBL24582713 | 0.79 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL3208272 | 0.79 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536163-A1 | AROMATIC PYRROLIDINE AND THIAZOLIDINE AMIDES | PFIZER INC. (US) | 1993-04-14 | — | — | EP | disclosed |
| WO-1991018891-A1 | AROMATIC PYRROLIDINE AND THIAZOLIDINE AMIDES | PFIZER INC. (US) | 1991-12-12 | — | — | WO | disclosed |