SCHEMBL95374

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4491643	0.86	TDP1 (0.75)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL1490952	0.85	HPGD (0.76)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL6023593	0.84	TDP1 (1.00)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL2422719	0.84	TDP1 (0.73)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL13212973	0.84	TDP1 (0.73)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL1394361	0.83	HPGD (0.72)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL4672305	0.82	TDP1 (0.69)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL13762084	0.82	TDP1 (0.74)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL8404655	0.82	TDP1 (0.74)	TDP1MLYCDHPGDALDH1A1LMNA
	SCHEMBL8404654	0.82	TDP1 (0.69)	TDP1MLYCDHPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.