Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682441 | 0.86 | TP53 (0.32) | — | |
| SCHEMBL9423725 | 0.82 | CNR2 (0.39) | CNR2KDM1APGR | |
| SCHEMBL8960238 | 0.75 | CNR2 (0.34) | CNR2KDM1A | |
| SCHEMBL10365982 | 0.74 | TDP1 (0.44) | CNR2KDM1APGR | |
| SCHEMBL27300218 | 0.72 | POLB (0.34) | — | |
| SCHEMBL10365163 | 0.72 | CNR2 (0.49) | CNR2KDM1APGR | |
| SCHEMBL8931503 | 0.70 | CNR2 (0.33) | CNR2 | |
| SCHEMBL3032933 | 0.69 | CNR2 (0.49) | CNR2KDM1ACA2 | |
| SCHEMBL29253141 | 0.69 | KMT2A (0.33) | — | |
| SCHEMBL9478152 | 0.68 | CNR2 (0.32) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274066-B1 | BENZOTHIAZOLONES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5079368-A | Chemical intermediate for herbicides | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1992-01-07 | — | — | US | disclosed |
| US-4954525-A | POLYPRENYL ACID, AMIDE OR KETONE | EISAI CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4946961-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-08-07 | — | — | US | disclosed |
| US-4888045-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-12-19 | — | — | US | disclosed |
| US-4835183-A | Method of treating cancerous and precancerous conditions | EISAI CO., LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0274066-A2 | Benzothiazolones, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-13 | — | — | EP | disclosed |
| US-4655973-A | ANTICANCER AGENTS | EISAI CO., LTD. (JP) | 1987-04-07 | — | — | US | disclosed |
| EP-0054732-B1 | CONJUGATED POLYPRENYLCARBOXYLIC ACIDS AND THEIR DERIVATIVES AS WELL AS PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS | Eisai Co., Ltd. (JP) | 1984-06-20 | — | — | EP | disclosed |
| EP-0059258-A1 | Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases | Eisai Co., Ltd. (JP) | 1982-09-08 | — | — | EP | disclosed |
| EP-0054732-A1 | Conjugated polyprenylcarboxylic acids and their derivatives as well as pharmaceutical preparations containing these compounds | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |