Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538280 | 0.86 | KDM4E (0.41) | BACE1KDM4EEPHX2SCN4AMETAP2 | |
| SCHEMBL856453 | 0.77 | TLR7 (0.41) | BACE1KDM4EKCNH2TLR7 | |
| SCHEMBL5460532 | 0.75 | KMT2A (0.45) | BACE1KDM4EEPHX2SCN4ADYRK1A | |
| SCHEMBL30586443 | 0.71 | BACE1 (0.65) | BACE1KDM4EEPHX2SCN4AMETAP2 | |
| SCHEMBL10967442 | 0.71 | BACE1 (0.65) | BACE1KDM4EEPHX2SCN4AMETAP2 | |
| SCHEMBL2472075 | 0.70 | DYRK1A (0.39) | BACE1KDM4EEPHX2SCN4AMETAP2 | |
| SCHEMBL7164162 | 0.68 | BACE1 (0.39) | BACE1KDM4EEPHX2SCN4AMETAP2 | |
| SCHEMBL31327779 | 0.67 | NT5E (0.68) | BACE1KDM4EEPHX2SCN4ANPBWR1 | |
| SCHEMBL2709353 | 0.67 | NT5E (0.68) | BACE1KDM4EEPHX2SCN4ANPBWR1 | |
| SCHEMBL13641613 | 0.66 | KDM4E (0.63) | BACE1KDM4EEPHX2SCN4ANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311955-B1 | BICYCLIC PEROXIDE | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |